Innovation Scientist, RNA Sciences

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Summary

The Innovation Scientist is a motivated self-starter who is solution-focused, takes initiative, and can design and execute wet-lab experiments. The Innovation Scientist will be responsible for enhancing Vernal’s plasmid and RNA processes through innovative research and development. They will provide encouraging and supportive mentorship within the RNA Sciences group. 

Responsibilities

  • Initiate, execute, and finalize client work orders 
  • Develop and optimize RNA synthesis reactions 
  • Develop and apply analytical methods to RNA 
  • Design and review process initiatives and experiments 
  • Create and optimize plasmid and mRNA synthesis workflows 
  • Operate as a key player in cutting-edge research 
  • Report on project status and product critical quality attributes (CQAs) 
  • Compile & present on major findings and innovation initiatives 
  • Employ literature search, curation, and application towards innovation initiatives 
  • Provide valuable mentorship to inspire and assist innovative projects driven by Research Associates 
  • Enjoy the benefits of living in Vermont 

Required skills and background

  • Ph.D. in cell or molecular biology, biomedical or chemical engineering, biochemistry, or a related field 
  • 2-3 years in a post-doctoral experience
  • mRNA: synthesis and purification, working knowledge of mRNA biology (e.g., sequence, structure) 
  • Molecular biology: Polymerase chain reaction (PCR), qPCR, RT-PCR, molecular cloning (e.g. Gibson or Golden Gate), agarose gel electrophoresis 
  • Deep understanding and practical knowledge of the scientific method and selection of experimental controls 
  • High attention to detail including organizing, planning, executing, and documenting experiments 
  • Communication skills including protocol writing, working directly with clients, PowerPoint 
  • Must be authorized to work in the United States

Desired skills and background

  • Protein chemistry: polyacrylamide gel electrophoresis (PAGE), western blotting, other forms of immunoblotting (e.g. dot and slot blots), silver staining, AKTA or FPLC purification, Bioanalyzer 
  • Cell biology: cell line and primary cell culture maintenance, expansion, banking, transfection optimization 
  • Optimization through design of experiments (DOE, e.g. JMP) 

Diversity/Equal Opportunity

Vernal is an equal opportunity employer. We recognize the value of diverse, multifaceted approaches towards innovation and aim to incorporate diverse perspectives and experiences. We strive to build a safe, welcoming, and inclusive work culture. 

At Vernal, you will offer knowledge-based solutions to help us address the growing demand for mRNA, lipid nanoparticle (LNP) mRNA, drug screening, and ultimately clinical supply of mRNA.  Together, we will create the most integrated solution for mRNA vaccines and therapeutic R&D.  Vernal will become the only one-stop-shop for our clients’ and partners’ mRNA needs, from concept all the way to clinical trials.  The mRNA research associate or scientist will develop methods to synthesize, purify, and scale up mRNA.  As a startup, we are seeking adaptable, creative thinkers who can independently foresee gaps and opportunities and who take the initiative to solve problems with a sense of urgency.  We expect the work to be rewarding, fast-paced, and to offer ample opportunities to plan and create new solutions to help grow our business.  Vernal will pay a competitive salary with generous benefits including health, dental, and vision insurance.  Although hiring level will depend on experience, we expect to grow with our employees and are interested in a variety of backgrounds.

Vernal Biosciences is located in Colchester, Vermont, adjacent to Burlington which is home of the University of Vermont and the UVM Medical Center.  Check out https://www.helloburlingtonvt.com/ for more information. The Burlington area, set on the shores of Lake Champlain, features the best of two worlds:

  1. Multicultural hub with great schools, restaurants, breweries, shopping, arts, and an affordable cost of living
  2. Gateway to the Green Mountains including world class hiking, camping, bicycling, and alpine and nordic skiing

Please contact [email protected] with CVs or for more information