hEPO mRNA

From: $305.00

Vernal now offers catalog hEPO mRNA that has been optimized to produce high expression level of human erythropoietin, a hormone that controls red blood cell production and maturation (erythropoiesis). Naturally produced in the kidneys in response to hypoxia, EPO also plays a role in wound healing and displays neuroprotective effects in response to brain injuries. hEPO mRNA is a common choice of mRNA to test therapeutic potential of different LNP designs for protein replacement therapy to treat diseases including anemia, neurological, and hepatic diseases.

Concentration and integrity testing assays are provided as standard.

Variation SKU Price
5MG VRN-EPO-5MG $5,999.00
1MG VRN-EPO-1MG $1,673.00
500UG VRN-EPO-500UG $1,068.00
250UG VRN-EPO-250UG $610.00
100UG VRN-EPO-100UG $305.00

Vernal now offers catalog hEPO mRNA that has been optimized to produce high expression level of human erythropoietin, a hormone that controls red blood cell production and maturation (erythropoiesis). Naturally produced in the kidneys in response to hypoxia, EPO also plays a role in wound healing and displays neuroprotective effects in response to brain injuries. hEPO mRNA is a common choice of mRNA to test therapeutic potential of different LNP designs for protein replacement therapy to treat diseases including anemia, neurological, and hepatic diseases.

Vernal’s mRNAs are highly pure mRNAs that incorporate modified nucleoside (N1-methylpseudoUridine), Cap-1 structure, optimized codons and poly(A) tail to improve translation efficiency and reduce host cell immune response. Vernal’s mRNAs function as mature, fully processed mRNAs, and are ready for use in cells and animals.

Catalog #VRN-EPO
Gene NamehEPO
Origin/SpeciesHuman
AppearanceClear and colorless
Encoded ProteinHuman erythropoietin
FunctionGene Replacement
Codon OptimizationYes
PurityFragment analysis by capillary electrophoresis
Length857 bp
Base CompositionModified
Concentration260/280 absorbance ratio
BufferWater
Recommended StorageAt -70°C or below
Applicationprotein replacement therapy, LNP design testing
Other NamesEPO mRNA, hEPO mRNA, Erythropoietin mRNA
General Tips Thaw on ice. Avoid freeze thaws as much as possible, centrifuge and aliquot into use volumes. Take precautions to avoid Rnase, use Rnase free reagents and consumables with appropriate Rnase free technique.
Shipping ConditionsShip on dry ice at -70°C or below
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Test
mRNA Concentration
mRNA Integrity
dsRNA
Residual DNA template
5’ Capping Efficiency 
Endotoxin 
Residual Protein

For research use only. Not for use in humans. The purchase of Vernal products does not grant or imply any license under any patents or patent pending. Vernal does not grant or imply and license under any patent or patent pending. Vernal does not warrant that the use or sale of products will not infringe the claims of any patents or patents pending. The purchaser has sole responsibility for all and any use of Vernal products.